Discover the best of Florida's biggest city from beachside at Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area. This east Jacksonville hotel is less than 30 minutes from the corporations and cultural attractions of downtown Jacksonville and within a few blocks of Jacksonville Beach. The fairways shot by legends at TPC Sawgrass are within four miles of our Jacksonville hotel for the ultimate getaway. Take the whole gang to enjoy the waterslides and go-kart racing at Adventure Landing. Stroll Jacksonville Beach Boardwalk or cast off from Jacksonville Fishing Pier, only two miles from Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area.